Pdf Book Name: Harrison’s Hematology and Oncology 3rd Edition
Author: Dan L. Longo
ISBN-10, 13: 9781259835834,1259835839
Pages: 848 pages
File size: 121 MB
File format: PDF,EPUB
Download Harrison’s Hematology and Oncology 3rd Edition Pdf Book Description:
Harrison’s Principles o Internal Medicine has a long and distinguished tradition in the field hematology. Maxwell Wintrobe, whose work actually established hematology as a distinct subspecialty o medicine, was a founding editor o the book and participated in the first seven editions, taking over or tinsley Harrison as editor in chief on the sixth and seventh editions. Wintrobe, born in 1901, began his study o blood in earnest in 1927 as an assistant in medicine at tulane University in New Orleans. He continued his studies at Johns Hopkins rom 1930 to 1943 and moved to the University o Utah in 1943, where he remained until his death in 1986. He invented a variety o the measures that are routinely used to characterize red blood cell abnormalities, including the hematocrit, the red cell indices, and erythrocyte sedimentation rate, and defined the normal and abnormal values or these parameters, among many other important contributions in a 50-year career. Oncology began as a subspecialty much later. It came to li e as a specific subdivision within hematology.
A subset o hematologists with a special interest in hematologic malignancies began working with chemotherapeutic agents to treat leukemia and lymphoma in the mid 1950s and early 1960s. As new agents were developed and the principles o clinical trial research were developed, the body o knowledge o oncology began to become larger and mainly independent rom hematology. Informed by the laboratory study o cancer biology and an expansion in focus beyond hematologic neoplasms to tumors o all organ systems, oncology developed as a separable discipline rom hematology. This separation was also fueled by the expansion o the body o knowledge about clotting and its disorders, which became a larger part o hematology. In most academic medical centers, hematology and oncology remain connected. However, conceptual distinctions between hematology and oncology have been made. Differences are rein forced by separate fellowship training programs (although many joint training programs remain), separate board certification examinations, separate professional organizations, and separate textbooks describing separate bodies o knowledge. In some academic medical centers, oncology is not merely a separate subspecialty division in a Department o Medicine but is an entirely distinct department in the medical school with the same standing as the Department o Medicine. Economic forces are also at work to separate hematology and oncology.
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