Book Name: CLINICAL NEUROANATOMY brain circuitry and its disorders 2nd Edition
Author: DR. HANS J. TEN DONKELAAR
Publisher: SPRINGER NATURE
ISBN-10, 13: 9783030418786,3030418782
File size: 120 MB
File format: PDF,EPUB
CLINICAL NEUROANATOMY brain circuitry and its disorders 2nd Edition Pdf Book Description:
This is one of the best book to know more about CLINICAL NEUROANATOMY and you have to download and read for free. Knowledge of how the various parts of the CNS are interconnected to form functional systems is a prerequisite for the proper understanding of data from other fields in the neurosciences. Connections define the functions of neurons. Information flows along connections, growth factors but also viruses are transported along connections, epileptic discharges are spread through connections, and when they are deprived of connections, neurons pine away and may die through retrograde degeneration or through anterograde transneuronal degeneration. Neuronal death in amyotrophic lateral sclerosis, spinocerebellar disorders, various intoxications and atrophy in olivopontocerebellar degeneration progress through neuronal connections. The distribution of neurofibrillary tangles in Alzheimer’s disease may also progress in this way. Parkinson disease may begin in the caudal brain stem, years before affecting the substantia nigra,and then progresses rostrally to reach limbic and cortical areas. The basal nucleus of Meynert and the extended amygdala are involved in some of the most devastating neuropsychiatric disorders such as schizophrenia and Alzheimer’s disease.
This book is on brain circuitry (“systems anatomy”) and its disorders. It tries to bridge the gap between neuroanatomy and clinical neurology and emphasises human and primate data in the context of the many disorders of brain circuitry so common in neurological practice. Throughout the book, clinical cases are included to illustrate where normal brain circuitry may be interrupted and to what effect. These cases were kindly provided by the coauthors of the various chapters, Peter van Domburg and Akira Hori in particular, and by clinical colleagues, neurologists, neuroradiologists and neuropathologists.
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