Book Name: Janeway’s Immunobiology Ninth Edition
Author: Murphy, Kenneth. Weaver, Casey
Publisher: Garland Science
ISBN-10, 13: 9780815345053, 0815345054
Pages: 924 pages
File size: 55 MB
File format: PDF,EPUB
Janeway’s Immunobiology Ninth Edition Pdf Book Description:
Janeway’s Immunobiology is intended for undergraduate and graduate courses and for medical students, but its depth and scope also make it a useful resource for trainees and practicing immunologists. Its narrative takes the host’s perspective in the struggle with the microbial world a viewpoint distinguishing ‘immunology’ from ‘microbiology’.Other facets of immunology, such as autoimmunity, immunodeficiencies, allergy, transplant rejection, and new aspects of cancer immunotherapy are also covered in depth, and a companion book, Case Studies in Immunology, provides clinical examples of immune related disease. In Immunobiology, symbols in the margin indicate where the basic immunological concepts related to Case Studies are discussed. Ten ninth edition retains the previous organization of five major sections and sixteen chapters, but reorganizes content to clarify presentation and eliminate redundancies, updating each chapter and adding over 100 new figures. The first section (Chapters 1–3) includes the latest developments in innate sensing mechanisms and covers new findings in innate lymphoid cells and the concept of ‘immune effector modules’ that is used throughout the rest of the book. Coverage of chemokine networks has been updated throughout (Chapters 3 and 11). The second section (Chapters 4–6) adds new findings for cell recognition and for the targeting of activation induced cytidine deaminase (AID) class switch recombination. The third section (Chapters 7 and 8) is extensively updated and covers new material on integrin activation, cytoskeletal reorganization, and Akt and mTOR signaling.
The fourth section enhances coverage of CD4 T cell subsets (Chapter 9), including follicular helper T cells that regulate switching and affinity maturation (Chapter 10). Chapter 11 now organizes innate and adaptive responses to pathogens around the effector module concept, and features new findings for tissue-resident memory T cells. Chapter 12 has been thoroughly updated to keep pace with the quickly advancing field of mucosal immunity. In the last section, coverage of primary and secondary immunodeficiencies has been reorganized and updated with an expanded treatment of immune evasion by pathogens and HIV/AIDS (Chapter 13). Updated and more detailed consideration of allergy and allergic diseases are presented in Chapter 14, and for autoimmunity and transplantation in Chapter 15. Finally, Chapter 16 has expanded coverage of new breakthroughs in cancer immunotherapy, including ‘checkpoint blockade’ and chimeric antigen receptor (CAR) T-cell therapies. The teaching and learning resources for instructors and students are available online. The homework platform is available to interested instructors and their students. Instructors will need to set up student access in order to use the dashboard to track student progress on assignments. The instructor’s resources on the Garland Science website are password-protected and available only to adopting instructors. The student resources on the Garland Science website are available to everyone. We hope these resources will enhance student learning and make it easier for instructors to prepare dynamic lectures and activities for the classroom.
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